Emergency crews had to shut down westbound Interstate 10 at two separate locations Sunday night.
The first incident happened at 59th Avenue where a man jumped out of a moving vehicle and was struck and killed by another car, according to the Arizona Department of Public Safety.
The car's driver stayed at the scene and waited for police, DPS said.
The freeway was also closed at I-10 and Riggs Road, according to DPS.
Two tractor-trailers and another vehicle crashed, causing one of the semis to roll.
DPS said the drivers suffered minor injuries.
No other information was immediately available.
Stay with cbs5az.com and CBS 5 News as this story develops.
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